Please stand by. Your program is about to begin. [Operator Instructions] Good day everyone and welcome to today's ANI Pharmaceuticals, Inc. First Quarter 2025 Earnings Results Call. Please note this call is being recorded. After the speakers’ opening remarks, there will be a question-and-answer session. [Operator Instructions] It is now my pleasure to turn the conference over to Lisa Wilson.

Thank you, operator. Welcome to ANI Pharmaceutical's Q1 2025 Earnings Results Call. This is Lisa Wilson, Investor Relations for ANI. With me on today's call are Nikhil Lalwani, President and Chief Executive Officer; Stephen Carey, Chief Financial Officer; and Chris Mutz, Senior Vice President and Head of ANI's Rare Disease Business. You can also access the webcast of this call through the Investor section of the ANI website at anipharmaceuticals.com. Before we get started, I would like to remind everyone that any statements made on today's conference call that express a belief, expectation, projection, forecast, anticipation, or intent regarding future events and the company's future performance may be considered forward-looking statements as defined by the Private Securities Litigation Reform Act. These forward-looking statements are based on information available to ANI Pharmaceuticals Management, as of today and involve risks and uncertainties including those noted in our press release issued this morning and our filings with the SEC. Such forward-looking statements are not guarantees of future performance. Actual results may differ materially from those projected in the forward-looking statements. ANI specifically disclaims any intent or obligation to update these forward-looking statements except as required by law. The archived webcast will be available for 30 days on our website, anipharmaceuticals.com. For the benefit of those who may be listening to the replay or archived webcast, this call was held and recorded on May 9, 2025. Since then, ANI may have made announcements related to the topics discussed, so please reference the company's most recent press releases and SEC filings. And with that, I'll turn the call over to Nikhil Lalwani.

Thank you, Lisa. Good morning, everyone, and thank you for joining us. I'll start by discussing our first quarter performance and highlights, along with our updated 2025 guidance. Chris will provide additional color on our rare disease business, including our lead asset, Cortrophin Gel, and our retina assets, ILUVIEN and YUTIQ. Finally, Steve will review our first quarter results and updated 2025 guidance in more detail. Following our remarks, we'll take your questions. We had a very strong start to the year with record revenue, adjusted EBITDA, and adjusted EPS. The first quarter reflected particularly strong performance for our generics business, continued solid demand for Cortrophin Gel, and increased demand for our brand's portfolio. The top-line upside was partially offset by near-term factors impacting our retina products that I will expand on in a moment. We were pleased with the strength across our overall company. Based on our first quarter performance and favorable demand trends across genetics, Cortrophin Gel and brands, we are raising our 2025 guidance for total revenues and adjusted non-GAAP EBITDA. We now expect 2025 revenues of $768 million to $793 million, which represents growth of 25% to 29% over 2024 versus our prior guidance of $756 million to $776 million. We expect adjusted non-GAAP EBITDA of $195 million to $205 million -- sorry, 205 million, which reflects growth of 25% to 31% over 2024 versus our prior guidance of $190 million to $200 million. Steve will provide more specifics on our updated guidance later in the call. Turning now to our first quarter results. Total revenues were [$197 million -- $197.1 million] (ph), representing a year-over-year increase of 43% on an as-reported basis and 32% on an organic basis, driven by exceptional performance for generics, continued strong growth for Cortrophin Gel, and continued demand for our…

Thank you, Nikhil, and good morning, everyone. As Nikhil mentioned, we were pleased with the strong demand trends for Cortrophin Gel during the first quarter, which included continued momentum in adding new prescribers and robust growth among existing prescribers. We saw demand growth across all of our targeted specialties. In particular in ophthalmology, we saw the highest growth given by the efforts of our expanded dedicated ophthalmology sales team. Notably, the number of new initiated cases and new patient starts for Cortrophin Gel reached record levels in the first quarter, which is not typically a seasonally strong quarter for Cortrophin Gel or rare disease drugs in general. We completed the expansion of our portfolio sales team, which cover indications across neurology, nephrology, and rheumatology. Our new team members are quickly building momentum in both new prescriber ads and patient starts in their sales territories. The indications for acute gouty arthritis flares, which is unique to Cortrophin Gel among ACTH therapies, remained a strong driver contributing to growth in the prescriber base and patients on therapy. There were also new affordability options under the Medicare Part D redesign under the Inflation Reduction Act or IRA. As Nikhil noted, we continue to see Cortrophin gel on a strong multi-year growth trajectory. We believe the number of patients on ACTH therapy now is approximately half the level of patients on therapy when the category previously peaked in 2017. We also believe the addressable patient population for ACTH therapy could be many times larger than the previous high of eight years ago. Keeping this significant unmet medical need in mind, we continue to invest in and make progress on initiatives to strengthen and grow the Cortrophin Gel franchise. Part of these efforts include improving patient and physician convenience. In March, we announced the approval…

Thanks, Chris, and good morning to everyone on the call. I'll review our first quarter results and then discuss our updated 2025 guidance. ANI had a very strong start to the year, and our first quarter results form a strong foundation for the achievement of our increased full-year financial goals. We generated first quarter revenues of $197.1 million, up 43% over the prior year period. Revenues from Rare Disease and Brands were $94.1 million in the first quarter, up 50% from the prior year period as reported, and 25% on an organic basis, driven by growth in our Rare Disease franchise. Rare disease revenues were $69 million, up 87% from the prior year period. Revenues from Cortrophin Gel were $52.9 million, up 43% from the prior year period, driven primarily by increased volume on a record number of new patient starts. Revenues from ILUVIEN and YUTIQ were $16.1 million for the reasons that Nikhil and Chris just discussed. Revenues for Brands were $25.1 million in the quarter, a decrease of 2% from the prior year period. The first quarter benefited from continued elevated demand, consistent with what we have periodically achieved with this portfolio in the past, and similar to prior year levels of revenue achievement. Revenues for our generics and other segments were $103 million, an increase of 38% over the prior year period. Revenues for generics were $98.7 million, an increase of 41% over the prior year period, and 26% over the fourth quarter of 2024 due to increased volumes from new product launches, such as Prucalopride, and the impact of 2024 product launches. Now moving down the P&L. As a reminder, when I speak to our operating expenses for the purposes of this earnings call, I will be referring to our non-GAAP expenses which are detailed on…

Thank you, Steve. We're pleased with the strong start to 2025 and would like to thank you, our customers, suppliers, partners, investors, and the entire ANI team for their collaboration and significant contributions in delivering on our company's purpose of serving patients improving lives. With that, operator, I turn it over to you for questions.

[Operator Instructions] We'll take our first question from Gary Nachman with Raymond James. Please go ahead.

Thanks and congrats on the strong quarter. So, first on Cortrophin, how much should the pre-filled syringe help you? Do you think it could open up use a lot more because of the convenience? And what sort of benefit are you seeing from the additional 20 reps across the indications? Are you considering adding some more for any indications? And [indiscernible] announced a good quarter for [Axar] (ph). It seems like there's good market growth. What else can you do to try and differentiate Cortrophin? I thought the [base-four] (ph) study for acute gouty flares is really interesting, so there are other studies that you're considering to potentially do with either the existing indications or maybe some others down the road. And then I have a follow-up.

Good morning, and thank you, Gary, for your question. So first on the pre-filtration syringe, you know, As Chris mentioned in the prepared remarks, the early response from ACP is positive, as this reduces one step in the administration process for Cortrophin Gel. And we look forward to updating you on the progress. We have just launched the product in the market. While we got the approval or announced the approval in March, we just launched the product, you know, a couple of weeks ago. So look forward to updating you on the progress. The next question was on the 20 reps and how that's going. They were doing well. They have started getting traction with getting both new patient starts and new prescribers and enrollments, and we'll continue to build momentum as the year progresses. We keep evaluating high ROI efforts from the commercial side. So with regards to adding more, there's no intent to do that this year at this time. We will again keep evaluating high ROI commercial initiatives to keep growing Cortrophin, which we believe is on a strong multi-year growth franchise, as we've talked about several times. You're right that the third point was on the competitor. The competitor did announce a strong quarter as well as increase their guidance to high single digits. So if you add their guidance, and our guidance, the combined market is growing approximately 16%. If you take this at high single digits, if you take that at 7.5%, the combined market will grow at about 16%. We think that's great for patients and for prescribers because the number of patients on therapy today are, you know, still half of what it was at its peak. And from an epidemiological perspective, the number of patients that can benefit or the addressable market is, you know, 6 times to 8 times higher than the number of patients that were even being treated at its peak. So, you know, it's good for the category to have two players bringing options for patients and for prescribers. You then asked about differentiation. So we continue to invest to strengthen the franchise. You will remember that we launched the 1 ml vial. Now we've launched the pre-filled syringe to increase convenience, enhance convenience for patients and prescribers. And we continue to evaluate additional steps that we can take to enhance the convenience for patients and for physicians, and we'll look forward to updating you on that progress. And then Chris details some of the efforts on the evidence generation area, right, and the [GAUSS] (ph) clinical study that we're initiating later this year. And that those are as well as the data that we presented at ARVO on uveitis, I think that those are indications of the multiple different steps across commercial evidence generation, bringing new presentations to the market that we're investing in to continue strengthening and growing the Cortrophin Gel franchise that we believe is on a strong multi-year road trajectory.

Okay, great. And then just regarding ILUVIEN and YUTIQ, just given some of the challenges in the first quarter, just what gives you confidence you can accelerate the sales to get up into the guidance range for the full year? That's a pretty big step up. And I appreciate the steps that you're taking, but how long you think for those to really take hold over the course of the year. And then just talk about the turnover in the optho sales team. It actually didn't seem to Cortrophin in that segment, which you said was really strong in optho, and I'm curious why that wasn't the case. And just, you know, going forward, your outlook for optho . Thanks.

Right. Thank you again for your question, Gary. So first, you know, ILUVIEN and YUTIQ guidance for this year is $97 million to $103 million, of which 30% is outside the U.S. Therefore, ILUVIEN and YUTIQ in the U.S. accounts for, you know, under 10% of total company 2025 revenue guidance. So just to dimensionalize that. And that's what, you know, the different topics, the factors we spoke about. But when it comes to the guidance, our confidence in re-editing the guidance for ILUVIEN and YUTIQ at $97 million to $103 million is based on five factors. First, the performance outside the U.S., which is roughly 30%, is largely on track across the markets with direct – the 4 markets with direct commercial operation and the 17 markets where we work with partners. Next, the factor is driving our confidence related to U.S. Performance for the rest of the year. So first quarter results were low due to seasonality, seen for most branded drugs. The remaining three quarters will not have this. In fact, it will reverse in the fourth quarter. So that's one. Second, we made significant strides in working through the turnover and strengthening our sales force with best-in-class talent. As of today, only four vacancies remain and we'll be back to full strength during the second quarter, which will create additional momentum. Third, we're already seeing positive impact in April results from the bespoke commercial approach by region that we deployed, given the Medicare dynamics. And then last, we expect to see positive impact from a combination of our efforts, exploring alternatives for Medicare patients to the Part D pathway and restart in the back half of the year of some level of foundation support for Medicare patients. So, I think that – I think you also asked more about turnover. Well, look, we believe – we have a high-performance culture, and, you know, in the initial integration timeframe, it is typical to have a cross-calibration leading to organizational changes. We're adding best-in-class talent for from top ophthalmology and retina organization. As we approach, we followed in Cortrophin and we expect our sales team to be back to full strength during the second quarter. So that's the Salesforce turnover dynamic that we had in our combined ophthalmology Salesforce and then you asked about impact on PCG in ophthalmology. While on a smaller base, Q1 volume for PCG, for Cortrophin, in ophthalmology was 50% higher than in Q4, and we believe that the momentum will continue, right, as we have our full strength combined ophthalmology, rare disease ophthalmology, Salesforce in action. And we feel confident about the continued growth and the outlook for Cortrophin in ophthalmology.

All right, great. Thanks for all that color, Nikhil. Appreciate it.

Thank you, Gary.

We'll go next to Faisal Khurshid with Leerink Partners.

Hey, Nikhil. Thanks so much for sharing the question. I just want to ask, can you kind of drill in a little bit more to kind of the details on the commercial and access challenges that impacted ILUVIEN in the first quarter? And can you just explain a little bit, help us understand what you were or kind of how you're thinking about like working around that with like, you know, getting the spec pharmacy and like part D over part B. If you just like understand that a little bit. Thank you.

All right. Thank you for your question and good morning, Faisal. So the challenge is that there's a subset of patients that are on Medicare that require co-pay support to get therapy under Part B as an envoy. And due to lack of funding, and they get the support from foundations, and due to lack of funding, and they get the support from foundations, and due to lack of funding, you know, these foundations have not been able to provide co-pay support, right? And this is a dynamic that emerged in Q1. So, you know, HCP physicians took some time and retina practices took some time to understand the change, whether it would persist and how they would need to modify their approach and practice while keeping patients first always. And so, their response has varied across regions and we've spent the time to understand how they're responding. One other thing to clarify is that this dynamic impacts, you know, ILUVIEN and the DME market more, and therapeutics in the DME market more and has been laid out by other therapeutics in the DME market and much lesser degree NIU-PS or non-infectious uveitis in the posterior segment of the eye patients. So our team has spent the time understanding the HCP responses and granular impact to their workflows. And with that understanding, you know, we're exploring alternate paths to improve the access for the DME population. So for example, the Medicare patients with pharmacy benefit, they can avail of the affordability options where there's a cap on the co-pay and smoothing offer that the Part D offers. So under that approach, we're exploring how to have retina physicians accessing ILUVIEN through a specialty pharmacy. Is that a sufficient color, Fasil?

Yeah, that's helpful. And then I had one on Cortrophin gel. So, you've done well in this acute gouty arthritis, [indiscernible], kind of exploring some additional, like evidence generation there. Are there other opportunities for you to kind of like recreate this sort of like carve out success in like other indications or disease segments?

Yes, absolutely. I think across, you know, it goes back to the epidemiology, across disease, across indications, the number of patients that can benefit from the therapy are significantly higher than what we are -- than that are availing of this option are being treated today. And, as we've shared, 40% of our prescribers on Cortrophin were naive to ACTH and had never prescribed ACTH before. So we have confidence in our ability to get this treatment and this treatment option to more patients and prescribers. And so going back to your question, yes, there is an opportunity to, you know, to bring more focused commercial efforts in other therapeutic areas as we have done in ophthalmology.

Got it. Thanks for taking the questions.

Thank you, Faisal.

We'll go next to Vamil Divan with Guggenheim Securities.

Great. Thanks for taking the questions. And congrats on the quarter. So maybe one question was sticking to the ophthalmology side and then one on the generics. So on ophthalmology, I appreciate all the color you provided. You did mention the New Day trials completed now and synchronicity as you said you finished six months. Maybe can you just share your perspectives on sort of what you're hoping to see from those trials, as we wait for the results here and then what sort of impact could those have commercially on that business? And then on the generic side, you mentioned the Prucalopride 180-day facility. I'm just wondering if you can comment on how much of contribution that was to the generic performance in the first quarter, so we have a sense, for the second quarter as well. Thank you.

All right. Thank you for your question. Good morning, and thank you for your question, Vamil. So on NEW DAY, we are in the process of analyzing the data from the completed NEW DAY study. And if successful, it will allow physicians to consider ILUVIEN earlier in the treatment of DME. No, as we've described before epidemiologically, today we have less than 5,000 patients annually on ILUVIEN, whereas the addressable market is, even before NEW DAY, is at 53,000, right, which is patients for whom multiple rounds of anti-VEGFs are not showing optimal response, and then they show positive response to steroid trial and can be considered for, they're then being considered for ILUVIEN. So that's the addressable market of 53,000 versus the 5,000 patients that are currently annually being treated on ILUVIEN. So the opportunity as it currently stands even before NEW DAY is pretty substantial. What NEW DAY will do is that much earlier in the treatment paradigm, right, so instead of 53,000, there are 400,000 additional patients that are being treated with multiple rounds of anti-VEGF. And so if NEW DAY is successful, it could, HCPs could consider using ILUVIEN earlier in the treatment paradigm. So it would open up a broader patient population for ILUVIEN. Next, your question on Prucalopride. Look, we don't comment on product level net revenues for the generics business. But what we can say is that our estimates show generalization levels significantly higher than the IQVIA reported TRx share of 62% to 63%. We're pleased with the execution of the ANI team on this product from R&D and regulatory to win the CGT approval against numerous competitors to the sales and marketing team's ability to launch this product and maximize the opportunity. We anticipate that Q2 for Prucalopride revenues will be down as compared to the first quarter, as the team will need to manage trade inventory levels down in advance of the end of 180 days of exclusivity on June 26th. So, you know, generics will be in Q2, will be slightly lower, as Steve pointed out, on the phasing perspective, will be lower than the first quarter and then return to growth in the subsequent quarters from a total company perspective.

Okay. All right, thank you.

Thank you, Vamil.

We'll go next to David Amsellem with Piper Sandler.

Thanks. So just a couple for me. First, on Cortrophin Gel, as the category returns to growth, do you anticipate the payer landscape becoming more challenging over time compared to where it is now. Just talk about payer dynamics and what you're anticipating with the category returning to growth. So that's number 1. And then number 2 is regarding ILUVIEN, I appreciate all the color on the headwinds, but I'm just wondering out loud how are you feeling about the underlying acquisition of Alimera and what has surprised you most in terms of the challenges that you faced with the asset. Thank you.

Thank you for your questions and good morning, David. So on Cortrophin, [pale landscape] (ph), remember this category had not seen competition for many, many decades. And the payers and PDMs, they definitely see us as the – they appreciate the fact that we brought competition to this category and, you know, we went to go and collaborate and partner with them from day one. So they appreciate that. And, you know, as the category has evolved and as we've grown, we've continued to collaborate with them and see, you know, see that continuing. I mean, at the end of the day, we all put the patients first and ensure that we're bringing this therapeutic, this much needed therapeutic to patients in need. So that's on the peer landscape dynamics. And then on, where do we, where's our head on the overall acquisition of ILUVIEN? I think the simplest answer to that is, you know, we just bought out a royalty obligation from SWK on ILUVIEN. And so we believe in the continued long-term opportunity for ILUVIEN and YUTIQ. So actually both in DME as well as in NIU-PS where the addressable markets are substantially higher. In DME, 5,000 out of 53,000. In NIU-PS, less than 5,000 out of 78,000 to 112,000. So large addressable markets, we're fully confident of our ability to solve problems. Even when we acquired Novitium, we had to work through certain challenges. And so you can see the value that the Novitium acquisition has brought to us. So this is a team that thrives on capturing opportunities and addressing challenges and has a very strong orientation towards problem solving. Last quarter when we were speaking, we were talking about the supply challenges related to the CMO for YUTIQ. And we've worked through that challenge, right? We're, later this quarter, we're going to start selling the combined label. So, I think it is -- as an operating team, we have a strong orientation towards problem solving. And as I said at the beginning, our belief in ILUVIEN is best highlighted by our recent, I think weeks ago, buyout of the royalty obligation from SWK. So thanks. Thank you for that question. We'll go next to Ekaterina Knyazkova with J.P. Morgan.

Thank you so much and congrats again on the quarter. So first question is just on Cortrophin. Can you elaborate a bit about which indications are driving most of the growth at this point? How much of the growth is coming from neuro versus rheumatology versus necrology versus some of the new areas like ophthalmology and just any changes you're seeing from a competitive standpoint on an indication by indication basis. And then the second question is just around tariffs. Do you think there's an opportunity for you to leverage your U.S. Manufacturing footprint if we do see these pharma tariffs enacted? And Just how much spare capacity do you have that you could potentially leverage to capture additional market share? Thanks.

Yeah. All right. Thank you, Ekaterina, for your questions, and good morning. So on the first question on the indications we're fortunate. We see growth across all specialties. You know, our core specialties, the ones that we launched with nephrology, rheumatology, and neurology, we see strong growth across those indications. You know, we talked about the -- more than 15% of our usage, of our Cortrophin usage is coming from gout. We see significant growth there too. Obviously, we invested in the expansion of our field force that focuses on nephrology, rheumatology, and neurology, and they do that together as a portfolio sales team. So that team, that expansion is yielding results. And then ophthalmology, while on a smaller base, showed the highest growth with almost 50% increase in volumes versus the fourth quarter. You know, pulmonology also continues to show growth. So really, you know, we have opportunities both across indications. And in terms of competitive dynamics, they've raised their guidance to high single digits and they spoke about four therapeutic areas that they're focusing their efforts on. And, you know, the category, the number of patients that can benefit is just much, much larger than what either competitor is treating at this time. So, yeah, I think both competitors can continue getting the ACTH therapeutics to more patients and continue to grow the market. And then your second question on tariffs and do we have spare capacity? Absolutely. We do have spare capacity across our plants in East Windsor, New Jersey, as well as in Baudette, Minnesota. We are positively in a relative to our pairs well positioned with over 90% of our revenues coming from finished goods manufactured in the U.S. And less than 5% direct reliance on China. And, you know, we'll play our role in, as we have done in the past, of -- if there is supply challenges that arise out of the [tariff situation] (ph) to provide therapeutics to patients in need. Thank you for your questions, Ekaterina.

[Operator Instructions] We'll go next to Les Sulewski with Truist Securities. Please go ahead.

Good morning. Thank you for taking my questions. So Nikhil, perhaps I'll start on Cortrophin. You mentioned the 40% percent naive patient adoption. Do you have a sense how those scripts for naive patients will have been trending over time? And I guess what point do you expect that figure to turn? And then as for the pre-filled syringe, is this driven by switches or naive patients? And what's the impact to margin profile from that product? And I guess more broadly, gross margin looks favorable in 1Q. How do you expect that to trend throughout 2025 and have a follow-up?

Yeah, good morning and thank you for your questions, Les. So, Cortrophin, you know, having 40% of prescribers that were naive to the category. That number keeps growing and we reach with a larger addressable market and reaching more HCPs. So we'll keep you updated on the progress on that. On the pre-filled syringe, we see the pre-filled syringe as another alternative, as we had the 5-ml vial and the 1-ml vial. So we're introducing the pre-filled syringe, which comes in two presentations, 1-ml and the [0.5-ml] (ph). And it's really for patients that have a, you know, that the reduction in the number of steps of administration will be helpful to them. So, you know, it's for a subset of patients. It's early days in the launch of the pre-filtration, so we'll update you regarding your question on switches and as a new patient or switches. We see this as another option for patients by reducing one step, for enhancing patient convenience by reducing one step in the steps for administration. And then in the newer term, we see limited impact on the margin profile. You know, it's priced at a slight premium to the 1 ml on a per ml basis, but with a limited impact. And then on gross margin evolution for the year, I'll turn it over to Steve to take that question.

Yeah, good morning, Les, and thanks, Nikhil. Yeah, as we cited on the call today, Les, we continue to anchor in overall company gross margin between 63% and 64% throughout the course of the year. And obviously there's numerous mixed elements as the year progresses. And we expect, as rare disease becomes a bigger portion of the overall part of the total company revenues in the second half of the year. And as the quarters progress, that will be a favorable margin input as compared to in the first quarter, you know, strong margins in generics driven by Prucalopride, as well as the persistence of market share gains in the brand business, which helped margins in the first quarter.

Great. That's helpful. As a follow-up on the ILUVIEN and YUTIQ, Nikhil, do you have a sensible portion of that subset as Medicare Part B? And is there a potential that cohort, I guess, of patients does not come back, given that, appears unlikely the third party will come back with funding, the assistance and co-pays? And then, I guess, the second portion, the Salesforce turnover within Ophthalmology, does that have any impact of Cortrophin or perhaps asked in another way, is that potential for an increase opportunity for Cortrophin given the new team that's in place now? Thank you.

Yeah. So Thank you for your questions, Les. So I'll take your second question first, which is on the turnover, you know, yes, I think you framed it correctly, appropriately, that if we had the full team staff, you would have seen more growth in Cortrophin. So yes, we will see the impact of the top talent that we bring in on both ILUVIEN and Cortrophin going forward. So that's the answer on the turnover and the positive impact on Cortrophin. And then your question on Medicare. So there's a subset of Medicare patients, right, that don't have copay support to various mechanisms that are available. And that's the population that's impacted by the funding not being available. And look from our perspective, you know, from everything that we've heard, from major contributors to the relevant foundations, seeing the public domain and the discussions with several stakeholders in retina we believe that some level of foundation support will return in the second half of the year. And if the foundation support does not come back, we're likely to trend towards the lower end of our guidance range as far as the ILUVIEN and YUTIQ is concerned. And remember, ILUVIEN and YUTIQ in the U.S. is about 70% of our total ILUVIEN and YUTIQ guidance, right? So from a total company basis, again just a reminder, it's less than 10% of total company 2025 revenues. And so our guidance for total company and the raise guidance factors in the books and takes across different business lines. And we have high confidence in the overall total company revenues and total company adjusted non-GAAP EBITDA and adjusted non-GAAP EPS guidance that we have given and we continue to retain that confidence. Thank you. Les.

Thank you. This does conclude today's question-and-answer session. I will now turn the program back over to Nikhil Lalwani for any additional or closing remarks.

Thank you everybody for joining our call this morning. We look forward to updating you on further progress as the year unfolds and we look forward to seeing many of you at the Jefferies Conference in New York in June. Thank you.

This does conclude today's program. Thank you for your participation. You may disconnect at any time.