Good morning ladies and gentlemen and welcome to the Insmed Second Quarter 2017 Financial Results Conference Call. At this time, all participants are in a listen-only mode. [Operator Instructions] as a reminder this call is being recorded. I'd now like to turn the conference over to your host, Blaine Davis, Head of Investor Relations. Mr. Davis, you may begin your conference.

Thanks, James. Good morning everyone, and welcome to today's conference call to discuss our second quarter financial results. I have recently joined the Insmed team as the Head of Investor Relations and look forward to working with all of you. As many of you know, we recently hosted an Investor day in New York City and I want to encourage everyone to review the content from that event. It is available on our website and also furnished on Form 8-K with the SEC. During the meeting, we conducted a Q&A session that provided additional details beyond our formal presentations. As of this moment, we do not have any new details to share with you and as a result we will not be conducting a Q&A session on the call today. In addition, following today's call, the company will remain in a quiet period until we release topline data from our Phase 3 CONVERT study which we expect to be in September plus or minus one month. While we acknowledge that some of you may have questions, we appreciate your understanding and look forward to reengaging with everyone once we've released the data. Before we start, let me remind you that today’s call will include forward-looking statements based on current expectations. Such statements represent our judgment as of today and may involve risks and uncertainties that may cause actual results to differ from the results discussed in the forward-looking statements. Please refer to our filings with the SEC, which are available through the SEC’s website at www.sec.gov or from our website for information concerning the risk factors that could affect the company. Joining me on today's call are members of the Insmed executive management team including Will Lewis, Insmed's President and Chief Executive Officer; and Paolo Tombesi, Chief Financial Officer. For today’s call, Will will provide a corporate update and then Paolo will briefly review the second quarter financials. At this time, let me turn the call over to Will.

Good morning, everyone, and thank you for joining us today. Insmed is on the verge of the most significant event in our more than 10-year history as a company as we expect to report the topline results of our Phase 3 CONVERT study in September plus or minus a month. As Blaine just mentioned, at this point, we have no new information regarding the release of data and therefore our guidance on timing remains the same. Positive topline results from the CONVERT study have the potential to put Insmed on a new trajectory of growth. To prepare for this important milestone and to showcase the depth of the talent at Insmed, we hosted an Investor Day in July. At this event, we shared an overview of our clinical development strategy for amikacin liposome inhalation suspension or ALIS, including the status of the Phase 3 CONVERT study and the follow-on 312 study. The FDA has recently advised Insmed that ALIS is the established name for our Phase 3 product candidate in development for the treatment of refractory NTM lung disease caused by MAC. This replaces what we've previously referred to as LAI. During the investor meeting we also had the opportunity to showcase the talent and the tremendous progress we have made over the last few years at Insmed. We've provided you with the details on our clinical development program, our commercial strategy, as well as our pipeline beyond ALIS. While there were many important areas of our business that we discussed, I wanted to highlight a few of them today. During the meeting we've provided you with extensive detail and background on the work we have done to better understand the potential size of the estimated addressable market in the U.S. and shared new information about the potential opportunity in…

Thanks, Will. Good morning, everyone. I am very excited to have joined the Insmed team in early June. It has been a busy few months since I have joined Insmed as we plan for the upcoming release of data and implementation of our strategic plans thereafter. I look forward to getting to know all of you as we move the company forward from here. Turning now to our quarterly results, this morning, we reported a net loss of $44.7 million or $0.72 per share compared with a net loss of $36.6 million or $0.59 per share for the second quarter of 2016. Research and development expenses increased to $26.9 million compared to $23.9 million in the second quarter of 2016. The increase was mainly due to an increase in expenses related to INS1007 and higher compensation and related expenses due to an increase in the headcount partially offset by decreases in ALIS manufacturing expenses. Second quarter G&A expenses were $16.6 million versus $12.3 million in 2016. The increase was mainly due to higher expenses related to our pre-commercial planning activities for ALIS and higher compensation related expenses due to an increase in headcount. As of June 30, 2017, we had cash and cash equivalents of approximately $91.1 million and our cash-based operating expenses for the second quarter were $38.2 million. Our cash operating expenses for the first half of 2017 were $69.4 million. These results are in line with our previously issued guidance for cash operating expenses for the first half of 2017 to be between $67 million and $77 million. A reconciliation of our GAAP operating expenses to our cash-based operating expenses is included in our press release which is available in the Investor Relations section of our website. As we have mentioned in the past, we plan to remain disciplined in our use of capital and to ensure our two priority programs, ALIS and INS1007 are appropriately resourced. With that, I’ll turn the call back to Will.

Thank you, Paolo. We are incredibly excited to be at this transformational point in Insmed's history as we work to build this company and prepare to share topline results from the CONVERT study. As many of you saw at our investor meeting we have an exceptional team capable of fulfilling this company’s mission. With that, I want to close the call by thanking all of you for the role you played in our success and your continued support and interest in Insmed. We look forward to reengaging with you following the release of topline data. Enjoy the rest of your summer.

This concludes today’s conference call. You may now disconnect.

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