Glenn Eisenberg
Management
Yes. Derik, I'd just add to that, maybe first with the backlog question. So a lot of things come into play. Obviously, the business mix that we have, the therapeutic mix, the stage of where the trials are, again, we have kind of the end-to-end business, if you will. Historically, plus or minus, we've been around 40% of backlog conversion. As Adam said, it's good to look at it on a kind of an annual basis because there's fluctuations. So we did see it drop down a little bit to the 37% from the quarter, but again, still in line. But as a general rule, maybe for modeling, if you will, we tend to say around 40% of conversion to revenues in the next 12 months, and that would represent roughly around 85% of the revenues for the next month. So another 15% comes in with, obviously, new business that's transacted during the year. On the Diagnostics margin standpoint, Adam really hit it well from the standpoint, while margins were down, again, excluding PAMA, we would have had nice margin appreciation. And in fact, the fourth quarter margins were down the least amount that they were all year, so as Launchpad is kicking in, as the growth of our underlying business is kicking in. And so while we still expect to see margins down next year -- slightly down because of another year of PAMA, we also similarly say we're -- not for PAMA, we'd actually be seeing nice margin appreciation. Our goal is to continue to manage our cost structure to do that. When we talk about higher personnel costs, that's kind of our way of every year saying personnel costs are our biggest cost. And so that does increase with normal inflation, and obviously, depending upon the markets that we serve. And so nothing, if you will, unusual about it other than that's just the biggest cost that we have to overcome.