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Bio-Techne Corporation (TECH)

Q3 2025 Earnings Call· Wed, May 7, 2025

$51.84

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Transcript

Operator

Operator

Good morning and welcome to the Bio-Techne Earnings Conference Call for the Third Quarter of Fiscal Year 2025. At this time, all participants have been placed in a listen-only mode, and the call will be open for questions following the management’s prepared remarks. During our Q&A session, please limit yourself to one question and a follow-up. I would now like to turn the call over to David Claire, Bio-Techne’s Vice President-Investor Relations. Please go ahead.

David Clair

Management

Good morning and thank you for joining us. On the call with me this morning are Kim Kelderman, President and Chief Executive Officer; and Jim Hippel, Chief Financial Officer of Bio-Techne. Before we begin, let me briefly cover our Safe Harbor statement. Some of the comments made during this conference call may be considered forward-looking statements, including beliefs and expectations about the company’s future results. The company’s 10-K for fiscal year 2024 identifies certain factors that could cause the company’s actual results to differ materially from those projected in the forward-looking statements made during this call. The company does not undertake to update any forward-looking statements because of any new information or future events or developments. The 10-K, as well as the company’s other SEC filings, are available on the company’s website within its Investor Relations section. During the call, non-GAAP financial measures may be used to provide information pertinent to ongoing business performance. Tables reconciling these measures to most comparable GAAP measures are available in the company’s press release issued earlier this morning on the Investor Relations section of our Bio-Techne Corporation website at www.bio-techne.com. Separately, in the coming weeks, we will be participating in the BofA Securities, RBC Capital Markets, Benchmark, William Blair, Jefferies and Goldman Sachs healthcare conferences. We look forward to connecting with many of you at these upcoming events. I will now turn the call over to Kim.

Kim Kelderman

President

Thanks, Dave, and good morning, everyone. Thank you for joining Bio-Techne's Third quarter conference call. I'm pleased to report that we delivered yet another strong quarter with 6% organic revenue growth, while operating in a relatively uncertain macro environment. Our differentiated performance was evident across our product portfolio, namely within our core reagents, our automated analytical solutions and in our cell and gene therapy offering. This result was once again delivered with an emphasis on profitability as the operational efficiencies we continue to put in place led to an adjusted operating margin of 34.9%. The team continues to do an excellent job of balancing investments to position the organization for future growth with initiatives to drive efficiencies. And by doing so, we are maintaining our industry-leading profitability. Our performance by end market in Q3 was led by low double-digit growth in pharma, which we expected to return historical growth rates in calendar 2025, following the realignment of their R&D pipelines during much of 2024. We saw early signs of this improvement in our fiscal second quarter with that positive momentum continuing into our third quarter. Going into calendar 2025, we did not anticipate the major US policy shifts impacting the academic end markets. This started on February 7, with the NIH issuing guidance of a flat indirect cost reimbursement rate of 15% across all NIH grants. With the incoming NIH Director announcing that he will be evaluating the impact of the proposed 15% cap, along with the federal judge implementing a permanent injunction on this policy, it remains to be seen how this will play out. In the meantime, however, our US academic customers are facing uncertainty around the future funding of their research projects. This can impact purchase decisions, particularly around capital equipment. Another policy shift that has been…

Jim Hippel

Chief Financial Officer

Thanks, Kim. I'll start with some additional details on our Q3 financial performance and then give some thoughts on the financial outlook for the remainder of the fiscal year. . Starting with the overall third quarter financial results. Adjusted EPS was $0.56 compared to $0.48 in the prior year with foreign exchange having an immaterial impact. GAAP EPS for the quarter was $0.14 compared to $0.31 in the prior year. Q3 revenue was $316.2 million, an increase of 6% year-over-year on an organic basis and 4% reported. Foreign exchange was unfavorable to revenue growth by 1% and divestitures also had a 1% impact to revenue. By geography, North America increased low-single digits year-over-year, driven primarily by our pharma customers. Europe increased mid-single digits year-over-year, led by strength from academic customers. And China decreased mid-single digits as the economic situation there is still challenging. Encouragingly, the rest of Asia increased mid-teens with our team executing very well on improving market conditions. By end market in Q3, biopharma increased mid-single digits, while academia was flat in the quarter. Below revenue on the P&L, total company adjusted gross margin was 71.6% in the quarter compared to 71.9% last year, down slightly due to unfavorable foreign exchange. Adjusted SG&A in Q3 was 29% of revenue compared to 30.3% in the prior year, while R&D expense in Q3 was 7.8% of revenue compared to 8.5% in the prior year. The decrease in SG&A and R&D was driven primarily by the benefit of structural streamlining and diligent expense control, which was partially offset by ongoing strategic growth initiatives. Adjusted operating margin for Q3 was 34.9%, up 190 basis points compared to the prior year due to the impact of favorable volume leverage, productivity gains and cost control partially offset by the impact of foreign exchange. We…

Operator

Operator

Thank you. Ladies and gentlemen, we will now be conducting a question-and-answer session [Operator Instructions] The first question comes from Puneet Souda with Leerink Partners. Please go ahead.

Puneet Souda

Analyst · Leerink Partners. Please go ahead

Hi, guys. Thanks for taking my questions here. Maybe the first one on the guide. Could you provide more context into that, Jim, in terms of the impact you're expecting on academic, I mean, it's a meaningful reduction versus what you had before. And what you're seeing in the quarter. So it does beg a question, was there a pull forward that you saw on the pharma side? And as a result, you're seeing more impact in the fourth quarter? Also on the pharma side, if you could clarify. I think you said low double digit at first, but then mid-single for biopharma. So could you just clarify what was the growth in pharma and large pharma?

Jim Hippel

Chief Financial Officer

I don't recall anything about biopharma, but so to clarify, large pharma was double-digit growth for the quarter. With respect to -- we think about Q3 versus Q4, Kim mentioned in his comments that we had -- our reagents, our quality of reagents are also sold to other life science tools companies or partners as, call it, ingredients into some of their products and we had some nice orders come from those customers who are largely serving from our customers as well this most recent quarter. And some of those orders we don't expect to repeat again necessarily in Q4. So that's going to be part of the reason for the step down in organic growth. But as it pertains to academia, we started our Q3 in academia very strong in January. And then, of course, in February, with all these announcements, there was a great slowdown in academia and then it kind of stabilized again in March. And we kind of expect that stabilization to occur or continue throughout -- throughout Q4, but thus be lower than where we were in Q3. I think the biggest question, and I think where we're being somewhat conservative, but I think prudent to be conservative on the pharma side. To expect double-digit growth in pharma in Q4 given the tariff environment that had been announced as of April 2, which is -- didn't really impact Q3 as much as it could Q4 is really, I think, one of the biggest difference in the guide is in Q4 versus how we performed in Q3. And then with regards to where our expectations were at the very beginning of the year, clearly, even though our performance year-to-date has more or less been in line with those expectations, how we got there is quite different, meaning large pharma has outperformed where we expect it to be up to this point in time. But clearly, we didn't expect a situation with the academic in the US policies. And then since you asked about smaller biotech or pharma, we talked about that being gradually gaining momentum in our first half of the year, but that momentum is somewhat stalled. It didn't go backwards, but it's somewhat stalled in Q3 and I think that's just a nature of the overall global economic uncertainties where our biotech customers are a little susceptible to that in terms of where our next dollar might come from down the road. So I think there's more highly sensitive to the more macro environment, and that's what we're seeing from them. So hopefully, that helps.

Kim Kelderman

President

Yes, Puneet, this is Kim. Good morning. Thank you for your question. And you mentioned pull forward, right? In Q2, we posted 9% organic growth, but I have mentioned that three of that were probably because of early demand by our customers. So we are very transparent in that. And this quarter, though, we do not see that. So we do not have a carve-out related to pull forwards. We do think this was really based upon momentum in the end market of large pharma.

Puneet Souda

Analyst · Leerink Partners. Please go ahead

Got it. That's helpful. And then since we're a -- fiscal year 2026 is around the corner, I'm wondering what you can provide there, just given a lot of -- I appreciate the uncertainty, but with China, NIH and with tariffs, appreciate you quantifying at least the gross impact, but how should we think about 2026? And just maybe a specific question on China, I believe it's 50/50 instrumentation and consumables for you there. How should we think about the China growth rate in 2026? Thank you.

Kim Kelderman

President

Yeah, Puneet. Yeah, 2026, we usually do a soft guide at the beginning of a fiscal year, which is about three months from now. And one thing that we feel relatively certain about is that we expect that there will be more clarity from the different headwinds in our end markets over those three months. It seems to be that, of course, a lot of turbulence has been installed upon NIH, as well as on the tariff situations, but we think that more clarity will come in coming months, coming quarters, and that will definitely help us quantifying the impact for biotech in the coming year. Your question around China, I think tariffs, as I mentioned in my prepared remarks, fortunately, are very negatable for Bio-Techne. I'm positive about how we can offset the tariff impacts and negate them. And we'll just have to see how the Chinese economy holds up and how their internal funding works. We definitely saw a little bit of a step back from our initial guide, right? So we had mentioned that China was stabilizing earlier in the fiscal year. We had mentioned that it would call back to the black and it was definitely on that trajectory. But this last quarter, with all the turbulence, you could certainly see a step back into mid-single digits negative. And that's very much driven by the tariffs and by the local economical activities.

Operator

Operator

Thank you. Our next question comes from Dan Leonard with UBS. Please go ahead.

Dan Leonard

Analyst · UBS. Please go ahead

Thank you. My first question is on tariffs. I would love to understand your exposure a bit better. I mean China is 9% of your revenue. And I think you quantified the analytical instrument exposure into China. But as Puneet mentioned, you saw more than analytical instruments into China. And I would assume that most of that is manufactured outside of China. So any color commentary, Kim, you can provide on why that tariff headwind is not larger?

Kim Kelderman

President

Yeah. Dan, thank you very much for your question. Yes, China is 9% of revenues. That's a good point. Usually, right, over the last couple of years, it was 50/50 if it comes to the mix between consumables and instruments. Over the last year, that has actually shifted a little bit. So that's not the real ratio anymore. But nonetheless, we -- let's say, it's 50% on our instruments. We have a very clear and fast pathway to be able to move some of the instrumentation manufacturing that we right now have in the US to another location, and that's the benefit of having a global footprint. Another Bio-Techne location that would be exempt from import fees into China. So that – and that is really the largest part of the tariffs. Our consumable part is vastly different if it comes to the tariffs. And we've actually, over the last couple of weeks, notice that we do not pay any tariffs on importing those. And that really negated most -- those two activities really negated most of the tariff exposure going into China.

Jim Hippel

Chief Financial Officer

If I could just add also the -- not all the all the instruments and cartridges for the instruments are produced in the U.S. today. So, it's not a one-for-one exposure. And it also allows for an easier transition of the instruments that are not currently made -- or that are currently made in the U.S. for China to allow those to be moved to the facility where there are instruments being made for China.

Dan Leonard

Analyst · UBS. Please go ahead

Understood. Thank you for that clarification. And then just a follow-up. Does the current tariff situation impacted all your thinking on having more of a local manufacturing footprint in China?

Kim Kelderman

President

Dan, I think it doesn't -- the tariffs have not changed our position there. We always had a mindset of China for China. And yes, actually, last year, we talked about Bio-Techne haven't opened a new facility in the Shanghai area to serve the Chinese market. And we're actually quite glad that we have this footprint because it might actually be a very, very -- will come in in handy the coming quarters as well, if necessary, right? But we are really happy with the layout as we have it because the local manufacturing in the different regions and therewith minimizing cross-border tariffs is definitely a tailwind right now.

Operator

Operator

Thank you. Our next question comes from Matt Larew with William Blair. Please go ahead.

Matt Larew

Analyst · William Blair. Please go ahead

I'll just circle back on the first question actually. As you really built the guide for this year, which I think you've called fairly well, it was exiting the high-single-digits. And the Street are used as a proxy for fiscal 2026. As you alluded, too much has changed. But to the point Jim on sort of lemons and lemonade, it feels like maybe the lemons are accumulating near-term and the lemonade it takes a little longer to squeeze out. So, at 8.5% street organic growth for next year and maybe the way you're guiding us for fiscal 2025, at least more reasonable starting point than the Street's at today?

Jim Hippel

Chief Financial Officer

Yes, I mean what I would say, Matt, is that what we're experiencing right now is very abrupt, but we also -- I think everyone hopes will be somewhat temporary, right? Our momentum going into Q3 was very strong. We're basically on our projections for on our projections for smaller biotech, we were and trajectory China. And academic was holding up very, very well as it had been consistently up until the last couple of months. And pharma was actually ahead of our expectations. So, it's really this temporary -- I call it, temporary jolt of uncertainty caused by proposed changes in policies and tariffs. And I think once that uncertainty is resolved and becomes more certain, almost regardless of what the outcome is, we will be extremely well-positioned to basically resume the trajectory that we were on. With -- now is that a quarter out or six months out or a year out, hopefully, we'll have more clarity in three months. But at some point, the uncertainty becomes more certain.

Matt Larew

Analyst · William Blair. Please go ahead

Okay. And then obviously, the margins were very strong, the strongest in a couple of years here. And year-over-year, that was mostly driven from spending leverage. I think OpEx up something like 5% year-to-date as the top line has recovered you've mentioned it in the comments, but can you just speak to sort of the tension between ongoing cost containment and investments and where you're seeing additional opportunities to drive leverage?

Jim Hippel

Chief Financial Officer

I mean the teams have been doing a great job actually for a couple of years now. And with regards to managing that balance between investments and cost containment alignment of our structure according to the various profiles of our business. And that has just basically continued. And we've been especially been diligent on the call discretionary cost side. The past three months or so, especially with the increased uncertainty that we've been seeing in our end markets. At a time of uncertainty is the last time that you want to shift gears with regards to accelerating investment or any kind of discretionary spend. So I think the out performance we saw in our margin was a combination of the revenues coming in as we had expected, but really holding back on the cost, seeing the kind of uncertainty build throughout the quarter that we did, just to make sure that we're extremely well prepared for fiscal year 2026 in particular, when these uncertainties start to become more certain.

Kim Kelderman

President

And I think it's the tension between -- it's not even tension really. We always said that we didn't want to get ahead of our skis if it comes to our cost position. So we have been very prudent, like Jim mentioned, the discussion are spend. But we also have been really focused on efficiencies, right? So we have management processes, a new company that we've definitely looked at and streamlined. We have integrated further some of our acquisitions to increase efficiencies. On the digital side, we have looked at ERPs and the different software packages for efficiency gains. And then last but not least, our operational processes and the margin boost from operations is also fantastic. So those have definitely been driving our results. And in the meantime, on the R&D side, we have a very, very detailed process, we call it characterization to really rank and stack all the investments in all the different R&D projects and make sure that we fund the ones that are of strategic importance and that have good returns investment. And we have a fantastic clarity on where to invest. And therewith, we manage the balance between the two very, really well.

Operator

Operator

Thank you. Our next question comes from Daniel Markowitz with Evercore ISI. Please go ahead.

Daniel Markowitz

Analyst · Evercore ISI. Please go ahead

Hey. Thanks for taking the question. The first one I had is based on the guidance, it seems like 4Q margins are expected in like the 32%-ish type range, and that's before tariff mitigation flows through. Is it fair to assume that fiscal '26 margins at that 4Q exit rate of about 32% makes sense? Or should we be more prudent, given the macro could imply that 26% organic needs to come down a few percent?

Jim Hippel

Chief Financial Officer

Yes, we're not going to comment on guidance for fiscal year '26 at this point in time, again, given all the uncertainties we're still dealing with. And so similar to the top line, hopefully, those uncertainties become more certain or less uncertain, three months from now, and we can provide some more direction than all I can share with you today is that I think this quarter demonstrated that we are positioning the company extremely well for whatever fiscal year 2026 brings from an end market perspective.

Daniel Markowitz

Analyst · Evercore ISI. Please go ahead

Great. And then just one follow-up. On A&G specifically, just using peer comments, it implies that the US academic and government end market could see like 10% to 15% incremental headwinds in calendar 2025. Is there any reason to believe this wouldn't be an appropriate way to think about it? Is it your exposure a little bit different? And then just what are the kind of cost offsets and a reasonable decremental margin profile on these US academic and government revenues?

Jim Hippel

Chief Financial Officer

Yes. I mean I can't comment specifically on the 10% to 15% except to say that our thoughts are this is that, first of all, the money that's largely being spent now by academic and probably for quarters to come from grants that we've already been approved and released. So we're really talking about the impact of probably calendar year 2026 and beyond with regards to whatever gets decided upon with regards to NIH budgets. And as a reminder, I think everyone understands this history, but I'll repeat it. This has happened before in a prior Trump administration where there were severe cuts proposed and a bipartisan Congress actually increased budgets every single year. So again, I think it's a bit overblown with regards to what the impact of budgets will be. But in the meantime, it's understandable that -- and we have several members of our Board who come from academia and there's -- of course, they've shared with us that there is a natural concern around us all this uncertainty and it causes distraction for them to -- as they think about where their next funds might come from for future grants. So that's why I think certainty as to where the budgets are at will be the most important thing to calm down the academic market. That all being said, much of the double-digit increases that have occurred in NIH funding over the past four or five years since COVID has been directed more towards infectious disease, vaccine development, things around COVID and such. And that is not our sweet spot where our portfolio plays. And so -- and we've heard the administration say they want to defocus those areas. And so if that's where the cuts happen, that will likely ultimately be much less, if any, impact to us and could actually be a tailwind, which is the Lmna [ph] I spoke of with regards to funds being redirected more towards traditional chronic diseases such as cancer, diabetes and neurology. And that's again where our portfolio strengths are. So that's how we think about it.

Kim Kelderman

President

Yes. And Daniel, thanks for the question. Let me add to that, that fortunately, Europe academics were really, really strong, right? So it's interesting to see that dynamic, which we might continue to see. But in the meantime, think about the -- our portfolio and how it also maps towards the academic market, Arguably, you would think that instrumentation is probably more impacted than our consumables. And we've seen that in our numbers. Our consumables at relatively flat in the US academic markets. 80% of our revenues come from consumables, 10% from services. And that's obviously a very favorable mix. If you then look at the other 10%, that's instrument related. Now these instruments are actually on a relatively low price point around $50,000, which then also you would expect is a little bit different decision-making process, so lower CapEx. But then in the meantime, they are positioned to automate very clunky yet fundamental processes in your laboratories and basically take cost out and increase your efficiencies which might be something that you really would like during times of constraints. So the positioning of those are just really, really, really good. And then last but not least, we're just really happy that we also have fantastic commercial excellence, right? So we have consultative selling from our team that a team of experts that can help you pick the right reagents really quickly and make sure that your experiments are repeatable and give you the right results. And in the meantime, for convenience, we have a very, very much a valued partnership with Thermo Fisher Scientific where we utilize the Fisher channels for ease of ordering. And with that, the academic market, we feel that are from all angles as well positioned as you could be.

Operator

Operator

Thank you. Our next question comes from Dan Arias with Stifel. Please go ahead.

Dan Arias

Analyst · Stifel. Please go ahead

Hi. Good morning guys. Thanks. Jim, I'm sorry, but I think I need to go back to the academic stuff here. You're calling out the headwinds there, which makes total sense, and then you're guiding organic down next quarter partially with that in mind. But I think your comment was that even under the most severe scenarios, funding would have an immaterial impact to getting to double-digit growth long term. So if the budget over the next couple of years is down 20%, 30%, 40%, which is in line with the proposal for 2026, is the idea that you can still get back to double-digits once the smoke clears on the other macro element? I think I just need a little help with how you're framing that over the 2026, 2027 period?

Jim Hippel

Chief Financial Officer

Yes, sure, Dan. Thanks for the question. So yes, I mean, at the end of the day, when you look around our strategic plan, the key academic is -- it's an important part of our business because it feeds into biotech and pharma, et cetera, it has never been the key growth driver for our plans. And our projections never assumed academic being a double-digit grower and more like a mid- single-digit grower, which it historically has been. And so quite simply, I took the details of our strategic plan and assumed the worst absolute worst-case scenario was a 40% cut in our academic revenue across the board. And then from there, a gradual increase to historical growth rates of 3% to 5% and we were still overall at a double-digit growth rate over a five-year period. So yes, I've taken that most severe situation into account in saying that it would still be a double-digit growth trajectory given our strategic plan.

Dan Arias

Analyst · Stifel. Please go ahead

Okay. Okay. Thanks for that. And then just maybe on cell and gene. Apologies if you did give it, but I didn't catch it. Is there a growth rate for the quarter? And just given what we're talking about, about some of the fluctuations in pharma ordering patterns, can you just sort of orientate us around what a good growth rate for GMP reagents, cell and gene would be for this year since it's pretty important to the model? Thanks so much.

Kim Kelderman

President

Yes, Dan, the cell and gene therapy product line, we talk about the trailing 12-months, right, and that was 30 -- a little over 30% for the 12-months period. And as you know, we had quarters where it was 90%, 60%, 10% and the swings in between, and that's just because the customers further along in the clinical process. So in Phase III, they order less frequently and larger orders, and that makes it lumpy. So that's why we always look at our 12-month trailing and that it's north of $30 million.

Operator

Operator

Thank you. Our next question comes from the line of Thomas DeBourcy with Nephron Research. Please go ahead.

Thomas DeBourcy

Analyst · Thomas DeBourcy with Nephron Research. Please go ahead

Hi, guys. Thanks for taking the question. My question is just on the Diagnosis and Genomics organic growth. I know you have more difficult comps in the second half of the year. But would have expected, I guess, Asuragen overall to kind of be more, I guess, unaffected by changes. And so just curious whether there's I guess, just timing issues related to some of the diagnostic and genomic portfolio?

Kim Kelderman

President

Thank you, Tom, for the question. I think that overall, in my prepared remarks, I mentioned that, of course, we looked very, very stringently at what is going on. And in detail, understand why the growth rate was lower than we usually have. But it was -- the diagnostic reagents division as well as Asuragen with the larger counters like I mentioned earlier, there's just a larger orders where timing becomes very important. So we definitely look by -- on a counter to account basis, are we losing share? Is the market slowing down and there's a clear no and no. So it was definitely a timing related dip for those two businesses, which is not uncommon. And that's why I look back at the year-to-date numbers for those two businesses, which are in both cases, healthy, high single and low-double for those two divisions. Our diagnostic test from the EPI point of view, the prostate test has been growing very nicely in line with the other quarters around 30%-ish for the year. And then last but not least, we have our Spatial Biology division, which has been seeing some headwinds from the NIH funding issues. That's the division that's mostly or most severely exposed to NIH market and certainly did not have the growth numbers that we've seen over the last couple of quarter, last couple of years. And there, we just look back at, do we have a fantastic offering? Are we competitive with our instrumentation. Do we win the deals that we compete in? And there also, everything is very, very healthy. It is a purely end market-driven headwind in that division. So that gives you basically the flavors of the four divisions in segment.

Thomas DeBourcy

Analyst · Thomas DeBourcy with Nephron Research. Please go ahead

Okay. Thank you.

Operator

Operator

Thank you. Our next question comes from Patrick Donnelly with Citi. Please go ahead.

Patrick Donnelly

Analyst · Citi. Please go ahead

Hi, guys. Thanks for taking the questions. Maybe one on the biopharma piece, I think you talked about mid-single-digit growth this quarter. Can you break that down a little bit? I just wanted to talk about the biotech piece in particular. I know you talked a little bit about GMPs, but can talk about what you're seeing from the biotech customer base certainly been a concern across the industry just given the volatility of the funding backdrop. So curious what you're hearing from the customers there and expectations on that front?

Kim Kelderman

President

Yeah. Thank you, Patrick. We certainly know that large pharma continues to be ahead of biotech in the recovery, right? Biotech is 30% of our revenues and large pharma 30%, and biotech was flattish in Q3. And we believe that biotech funding is, obviously, very sensitive to capital markets and those are very sensitive to economic uncertainty. And that typically leads to more frugal spending, and that's what we saw this quarter and that we expect next quarter.

Patrick Donnelly

Analyst · Citi. Please go ahead

Okay. That's helpful. And then if you don't mind, just a quick update on what's happening with Wilson Wolf, what the trends were this quarter. I just want to keep an eye on that as we go as well. Thanks.

Jim Hippel

Chief Financial Officer

Yes, Patrick, this is Jim. Thanks for the question. So, yes, Wilson Wolf continues to perform very, very well. They had growth very solidly into the double-digit growth rates this most recent quarter. So, they were projecting to have a very, very strong year in what will be calendar year 2025 for them going into calendar year 2026 and so far, they're right on track for that.

Patrick Donnelly

Analyst · Citi. Please go ahead

Thanks guys.

Operator

Operator

Thank you. The next question comes from Sung Ji Nam with Scotiabank. Please go ahead.

Sung Ji Nam

Analyst · Scotiabank. Please go ahead

Hi, thanks for taking the questions. Maybe if I could go back to pharma, biopharma, the sectoral tariffs that are under discussion. Just curious, I would love to hear your thoughts in terms of -- in an environment where there might be significant CapEx spending going towards U.S., expanding U.S. manufacturing reshoring, et cetera. by potential pressure on the early stage or early discovery development work. Just curious how Bio-Techne is positioned in that environment? Or if you have different thoughts in terms of how the tariffs could play out? Thanks.

Jim Hippel

Chief Financial Officer

I'll start off. This is Jim. Thanks for the question. I think part of the looming discussions we're hearing the administration around tariffs for pharmaceuticals is again, part of the reason for the guide that we did for Q4. I think there's going to be perhaps a level three right now, another level of uncertainty as it pertains to our pharma customer base. And so we've seen how uncertainty impacts other parts of our end markets. So, we kind of expect the thing for pharma at least temporarily. I don't know. It's probably anyone's guess as to how it ultimately plays. That's -- it's hard to put out different scenarios when we don't even know what the proposal is going to be with regards to tariffs in our pharma base. But I would say this, pharma spent a good part of last year already realigning their pipelines for what was the IRA Act. And that's not something they do take lightly, and it's a pretty great large endeavor. And for the most part, what we're hearing from our customers is that's behind them. So, I think there'll be -- there clearly going to be some changes with regards to CapEx spend and so forth. But at the end of the day, the pharma companies overall are flushed with cash. They're overall doing very, very well. And just because they need to perhaps spend some more on CapEx because that's what they need to do to move some manufacturing lines around. It doesn't necessarily mean that that they'll cut out of their -- take that out their P&L for R&D. But it's a good question, it remains to be seen.

Kim Kelderman

President

Let me add to that. Overall, I mean, the early-stage Bio-Techne with the core reagents was very much research-oriented. But over the years, we have definitely diversified our portfolio, make sure that we can continue to join a customer in their downstream processes into clinicals and into eventually a treatment. So, we have now our products way more distributed along the different stages. And you can see that in some of our presentations, where we definitely play in discovery all the way through manufacturing and of course, also have a portion of our company aligned with the diagnostics and treatment of the diseases. So, our portfolio is much more distributed than it has been a long time ago. So, that means that even though there might be some shift in where the pharma spending is, we feel that we're nicely distributed and therefore, will benefit from the overall spend level.

Sung Ji Nam

Analyst · Scotiabank. Please go ahead

Got it. That's helpful. And then just quickly on the Spatial Biology side, thanks for the color there and the exposure to the academic market, I was wondering about academic market outside the U.S., whether Spatial could be growing faster? And then also the recent launch of spatial protein proximity detection capability. I was curious if that could be also -- could be utilized within pharma? And kind of if you could talk about the competitive dynamics there for that particular application. Just not familiar with it. Thank you.

Kim Kelderman

President

Well, thanks for noticing it. Yes. So I do believe, especially from an instrumentation point of view, where we still booked double-digit growth. As I mentioned, we certainly look at our win/loss rates, and we're really happy where those sit. So we know that we're not losing share. And if anything, we're really -- we're doing really well with our placements and a very competitive offering. As you noticed, we have an instrument that is fully automated, it can run through multiomics it will pull through our antibodies as well as our RNA scope for the RNA detection. And then the -- on the consumables side, we now have the capability of not only show your proteins as well as the RNA but then also protein proximity, meaning protein-protein interactions, which it can be extremely important in the development and the treatment of a disease. So you can see that we've been building out a multiomics where there's truly no competitor already looking at just RNA and proteins. And now we're adding RNA proteins and protein interactions. So that's truly unique if it comes to the offering and very high value to our customers. So we're very pleased with our competitive positioning there.

Operator

Operator

Thank you. That was the last question for the day. I would now like to hand the conference over to Kim Kelderman for closing remarks.

Kim Kelderman

President

Yeah. Thank you very much for your insightful questions. And before we conclude the call, I'd like to formally welcome Dr. Amy Herr the Board of Directors of Bio-Techne, Dr. Herr is currently a Chancellor's Professor of Bioengineering at the University of California, Berkeley, and she also serves as the Vice President of the Zuckerberg Biohub Network. Dr. Herr's appointment completes a two-year process to identify and appoint successors to retiring director Randy Steer, who retired in 2024 and Dr. Roeland Nusse, who will be retiring later in 2025. Dr. Herr's, deep biological and engineering experience are an ideal fit for our Board of Directors and the strategic direction of the company. Welcome, Dr. Herr. And to conclude the call, I want to say that I'm extremely proud of the team's continued execution in what has proven to be a prolonged period of uncertainty in our end markets. Our differentiated financial performance is a testament to the value our customers place on our uniquely positioned portfolio of research reagents, proteomic analysis tools, cell therapy workflow solutions and diagnostics and special biology products. This portfolio unlocks cutting-edge discoveries and significant efficiencies for our customers. It also provides a strong foundation to sustainable value creation within Bio-Techne, while we pursue our mission to improve the quality of life by catalyzing advances in science and medicine. Thank you very much for attending our call, and have a great day.

Operator

Operator

Thank you. This concludes today's teleconference. You may disconnect your lines at this time. Thank you for your participation.