Good morning, ladies and gentlemen. Thank you for standing by. And welcome to the UroGen Pharma’s First Quarter 2021 Financial Results and Business Update Conference Call. It is now my pleasure to turn the call over to Lee Roth of Burns McClellan. Please go ahead.

Thank you, Jonathan. Good morning, everyone. And welcome to UroGen Pharma’s first quarter 2021 financial results and business update conference call. I’m filling in for Sara Sherman, Head of Investor Relations at UroGen, who’s on maternity leave. Earlier this morning, we issued a press release providing an overview of our recent corporate highlights and financial results for the quarter-ended March 31, 2021. The press release can be accessed on the Investors portion of our website at investors.urogen.com. Joining me on the call today are Liz Barrett, President and Chief Executive Officer; Jeff Bova, Chief Commercial Officer; Dr. Mark Schoenberg, Chief Medical Officer; and Molly Henderson, Chief Financial Officer. Please note that we continue to conducting our calls from different locations, so we appreciate your patience and understanding should we have any technical difficulties. During today’s call, we will be making certain forward-looking statements. This may include statements regarding the success and timing of our ongoing commercialization of Jelmyto commercialization, planned clinical trials, data presentation, regulatory filings, future research and clinical development efforts, manufacturing capabilities and 2021 financial guidance among other things. These forward-looking statements are based on current information assumptions and expectations that are subject to change. A description of potential risks can be found in our earnings press release as well as latest SEC disclosure documents. You are caution to not to place undue reliance on these forward-looking statements and UroGen disclaims any obligation to update these statements. With that, it’s my pleasure to turn the call over to Liz.

Thank you, Lee, and thank you to everyone joining us today. While it has only been eight weeks since we hosted our fourth quarter and full year 2020 earnings call, we have continued to make important progress towards our goal of becoming the leading uro-oncology company. Our ongoing priority is the successful commercialization of Jelmyto. Despite facing the unique challenge of launching during a global pandemic, Jelmyto’s place in the clinic continues to take shape as the only FDA approved non-surgical treatment for adult patients with low-grade upper tract urothelial cancer. For the first quarter of 2021, we recorded $7.5 million in net product sells. This brings us to a total of $19.3 million in sales since the June 1, 2020 launch of Jelmyto. As mentioned during our year-end earnings call in March, we experienced softness in the beginning of the quarter, which we attribute to the start of the vaccination efforts throughout the United States and patients specifically within the age group that are most likely to suffer from UT UC. We're delaying treatment appointments until they were vaccinated and felt comfortable going to a healthcare facility. As you have undoubtedly heard as numerous companies report earnings, this impact was seen across the biotech, pharma and medical device industries. Jeff will provide more detail in a bit, but we are confident in our outlook for Jelmyto for the remainder of 2021 and beyond. Due to the increase in patients treated in March and April, and the record number of patient enrollments we received over this same period. We believe the increased demand is driven by the fact that a large percentage of our patient demographic has been vaccinated and COVID-related restrictions or relaxing in many parts of the country. While we have not provided specific financial guidance, we reiterate…

Thank you, Liz. I'm pleased to provide you with an update on our commercial launch of Jelmyto. As Liz mentioned, we reported $7.5 million in net product sales in the first quarter of 2021, which totals to $19.3 million from the start a Jelmyto’s launch on June 1, 2020. Please keep in mind as we discussed in March that about $500,000 to $800,000 of sales in Q4 were stock ups that we'll work through in the January-February timeframe. When you take this into account, Q1 surpassed Q4 in terms of patient demand. As noted earlier, the COVID-19 pandemic have presented challenges to our industry. At the beginning of the year COVID infections and hospitalization spiked across the country. Vaccinations were still in the very early stages of rollout. And this created a situation where we believe that patients postponed doctor and treatment appointments. This was happening across our industry as evidenced by a recent Kaiser Family Foundation study that reported 25% of Americans said that they or someone in their household had delayed medical care in December due to Coronavirus concerns. Another report from the U.S. Centers for Disease Control and Prevention found that 41% of Americans delayed medical care, including 12% who postponed urgent or emergency care. And lastly in January elective procedures were down 25% according to IQVIA data. We believe the impact of patients postponing treatments until they are vaccinated is generally behind us given that the vast majority of people in the U.S. over the age of 65 which is our patient demographic are now vaccinated. In fact, as of today, 83% of the U.S. population over the age of 65 have received at least one dose of COVID vaccine and close to 70% have been fully vaccinated. With market conditions improving we are seeing a…

Thank you, Jeff. Since our last quarterly call, we've continued to make progress on our UGN-102 program for patients with low-grade intermediate risk non-muscle invasive bladder cancer. We are enrolling patients in our Phase three ATLAS trial, with about a third of the trial sites in the U.S. a handful in Israel and the remainder in Europe, primarily Eastern Europe. We look forward to providing you enrollment updates for ATLAS in the second half of this year as we work to bring this investigational treatment to patients. In addition to ATLAS, we are planning to initiate a small single arm at-home installation study of 102, with a goal of demonstrating that at-home installation is a feasible method of administration and further reinforcing its potential differentiation from to TURBT. We plan to enroll approximately 10 patients who would receive UGN-102 administered by a qualified home health provider. This study is expected to initiate in the second half of 2021. As you know, our goal with UGN-102 program is to demonstrate that a non-surgical therapeutic alternative can function as primary therapy for low grade intermediate risk non-muscle invasive bladder cancer patients. Importantly, a non-surgical option would help patients avoid the risk of potential complications that come from the current treatment approach, which is repeated to TURBT procedures. Dr. Gary Steinberg and I recently had a manuscript published in the Journal of Urology, which highlighted the challenges associated with repeated TURBT, including the high rate of disease occurrence, as well as the risks and complications of the procedure. The manuscripts which is currently available online and will be in the July print edition of the journal addresses the desire of both patients and physicians to identify non-surgical alternatives to TURBT for recurrent NMIBC. We also recently received notification that the AUA accepted multiple…

Thank you, Mark, and thank you to everyone who joined today's call. As mentioned, we recorded net product sales of Jelmyto for the first quarter ended March 31, 2021 approximately $7.5 million. Although this was a slower start in 2021 than we had initially anticipated, we are optimistic with respect to revenues for the remainder of the year. As Jeff mentioned, we have set new records and patient enrollment forms in March and April. And April was our strongest month yet in terms of both new patients starts and shipments. Cost of revenues for the first quarter of 2021 were approximately $0.9 million resulting in a gross margin of 88%. In periods prior to receiving FDA approval of Jelmyto, we recognized inventory-related costs associated with the manufacturing of Jelmyto as research and development expenses. We expect this to continue to impact cost of revenues through the second quarter of 2022 as we produce Jelmyto at cost, reflecting the full cost of manufacturing. And as we deplete inventories that we had expensed prior to receiving FDA approval. Gross margin would have been approximately 85.6% versus the 88% for the three months ended March 31 2021, if we had not sold Jelmyto that were expensed prior to regulatory approval, Research and development expenses for the first quarter ended March 31, 2021 were $10.5 million compared to $16.6 million for the same period in 2020. R&D expenses declined $6.1 million in the first quarter of 2021, compared to the first quarter of 2020, due to a onetime payment of $6.6 million to the Israel Innovation Authority to unwind our obligations regarding grants that were loaned to the company between January 20, 2004 and September 2016. Other than the commitment to continue at least 75% of our R&D jobs in Israel for a period…

Thank you. [Operator Instructions] Our first question comes from Eric Joseph with JPMorgan. Yourline is now open.

And good morning. Thanks for taking the question. This is Hannah on for Eric. Just a few from us. First looking at the soft sales from the last quarter. As things start opening back up, do you anticipate that you might be seeing any patient warehousing impacts from the pandemic? And therefore any potential for a bolus effect in second quarter in third quarter that might not be reflective of the subsequent quarters?

Hi, it’s Liz. Thanks for the question. I think what we have already seen and what we've talked about on this call, is we've already seen an uptake. I would not call it a bolus. And I'll ask Jeff to comment as well. One big bolus that you would actually see go down. But I think what we're seeing is very consistent higher patients coming in. So Jeff, do you want to add anything to that?

Sure. So we see steady growth. So I would agree with Liz. You just don't see a significant bolus. But as offices are opening up, patients are getting vaccinated patients are coming in to get treated, we're starting to see that steady growth. And then even the access to the representatives. Obviously in an orphan drugs setting patient identification is key and our reps are the face of Jelmyto. And so having them in there help identify additional patients. Again, not a bolus effect, but a steady increase in patients coming in Q2-Q3.

Okay, thank you. And also, just looking at the breakdown between retreatment sites versus newly treating sites in terms of the proportion of treated patients. Do you see retreatment sites picking up in that respect? For example, treating a larger proportion of patients compared to before? Or is that breakdown in terms of percentages remaining more or less steady?

No, I see that increasing -- yeah, I see that increasing as well. You're starting to see multiple patients in one account. The other thing that we're starting to see are multiple physicians in that account. I always talk about that peer-to-peer interaction, being a second wave of launch. And we're starting to see that number of grow as well. And we'll continue that.

And if I could -- thank you so much. If I could just one more. So you've guided to SPS [ph] regulatory updates in the second half of 2021. But while you might not be able to provide outcomes at the moment, just wondering what regulatory agencies we've been speaking to? And what those topics of conversations and things before?

So we haven't had any regulatory outside of the U.S. Obviously, I don't think we talked at all about regulatory updates. What we said was that this kind of midyear, we would know more about what we needed to do to launch around the world. And part of that is obviously talking to regulatory agencies. But it's also, understanding what clinical studies we might need to do. So there's more than just regulatory. So we're an ongoing dialogues in the U.S. on many things, right? We're have our IND for our 302 program. And we're always talking to them about UGN-102. And making sure that we're covering all our bases there from a standpoint of maybe other populations that we might be able to study. So we have an ongoing dialogue with the FDA. We do have upcoming, meetings in both Europe and Japan. That will give us more of an understanding of exactly what needs to for us -- exactly what we need to do to launch in those space in those geographies. But those as we said, would be kind of midyear timeframe, we'll be able to get a better idea of what's happening ex-U.S.

Okay, great. Thanks so much for taking the question.

Thank you. Our next question comes from Chris Howerton with Jefferies. Your line is now open.

Great. Well, congratulations to your team, Jeff. Really a good quarter from my perspective, and nice to see. So I guess with respect to kind of the performance that we're seeing overall there. What -- I think you said in your prepared remarks, something along the lines, that 1Q is outperforming patient demand. If you could just walk us through those numbers, relative to what you saw in fourth quarter, I think that would be really helpful. And then the second question I have is for Mark. I guess I'm curious if you could just give us a little more color as to what the expected presentations might be at AUA? And in particular, I'm interested if you have any analysis of recurrent rates for the TURBT procedure in the intermediate risk patient population. Thank you.

So Jeff wanted to take that first and then Mark can chime in.

Sure. Thanks, Chris. So to put some light on what happened at the end of the year, so what we had were a handful of accounts that because of I think everyone can relate to the shipping issues the other the demand from Amazon and FedEx and everything else. We had a handful of accounts that ordered a bulk amount. So they ordered the six doses, they wanted to be sure that they had the accounts. We had, obviously a lot of weather issues in FedEx hub in Tennessee. And so the 500 to 800 would have been reflected in Q1. Therefore, Q1 demand was actually higher than Q4. So most accounts, in fact, 95% the order one at a time, what we saw at the end of the year. Because all the issues we were having weather related and then package demand accounts order more than one. Hopefully that helped.

Yeah, okay, I got it.

Chris, thanks for the question. And I have to apologize in advance. I can tell you generally that we've been focused, as you know on getting a better understanding of the actual course, and experience in patients with intermediate risk disease. And so a number of the abstracts will, in fact address at a granular level. Some of that information which comes from the very good contemporary database. In addition, there will be some very specific information presented about patient experience and patient attitudes towards surgery. Unfortunately, I can't be more specific because the abstracts are actually embargoed. But I hope that's helpful, at least giving you a sense of where these presentations will go directionally.

Yeah. Okay. Yeah, that is helpful. And I guess, do you know any more timelines in terms of when the abstracts or whatever would become available? I know you said the meeting is in September.

Yeah. Historically, the abstracts have become available, I believe, about three or four weeks before the meeting. But I'm sure that we'll be able to provide more updates. Because it's been a bit of an unusual year in terms of the scheduling of the AUA -- the format presentations. It's a little hard to predict. But if history is any guide, it'll probably be sometime in August.

Okay, well, awesome. I very much look forward to that. Thank you.

Thanks, Chris.

Thank you. Our next question comes from Ram Selvaraju with H.C. Wainwright. Your line is now open.

Hi. Thanks so much for taking my questions and congrats on all the progress. Can you hear me?

Yes, we can. Thank you.

Okay, so firstly, question for Liz on strategy. I think you were talking earlier about regulatory interactions in ex-U.S. territories. Can you discuss a little bit the overall plan with respect to Jelmyto, UGN-101’s penetration into ex-U.S. territories? How you're viewing the most expeditious and optimal, effective, efficient way of doing that, whether that's going to be via partnerships or distribution arrangements? How your thinking has evolved over time since the Jelmyto launch in the United States?

It's a great question. I think we're obviously thinking about it opportunistically. I think we feel like, likely we would not commercialize ourselves ex-U.S. And, we've looked at it, but it will likely partner. We have had a lot of interest in like individual regions. But -- so we're considering whether it makes more sense to have 102 larger partners that can cover more geography. Or are we willing to sort of take more regional deals. I think at this point in time, we've decided that the freedom to operate and to maintain fewer partners ex-U.S. is probably the better route for us. Because if you start to think about just the distraction and the individual countries for Jelmyto, again being an orphan drug. Now, as we started to think about 102 that could easily change. But at this point in time, we have had interest in Europe. We've had interest in Japan, we've had interest in China, we've had interest in Latin America; we've had interest in Canada. And so what we have to do first is find out exactly what it's going to take. Because before we could do a deal with a partner. We need to understand what has to get done in those regions. And, as we've talked about before, a small company we didn't have the resources to really spend there. But we are doing that now. So we have interactions upcoming as I mentioned, both with Europe and Japan. And after that, then will more increased the conversations that we’ve been having with some of our partners, after we understand that we've had a lot of interest in China, as you can imagine. And so that's -- so I think the first step is for us to know exactly what the plan is, and then to discuss with potential partners, what that might look like. But I think if we have our -- if I had my preference, I think I'd rather have fewer partners with more geography. I think, to one area, that we've may feel differently about Israel, which is not financially doesn't matter so much, isn't significant. But frankly, we are Israeli-based company. And we think it's important for us in the Israel positions and institutions were part of this studies, since we started. And so we are looking to try to commercialize in Israel as quickly as possible. Either ourselves, we could do it or through a partner there. So we're working on that as we speak.

Okay, and then just a couple quick questions. I don't know whether these are more addressable by Jeff or by Mark, perhaps by both. If we can start with the at-home installation potential for UGN-102. I was just wondering if you could provide some more color on the degree to which this might be commercially impactful presentation of the drug and also the extent to which you're already seeing interest in this presentation, this context from both patients and physicians. Thank you.

Yeah, I think I'll just take that because it's just easier. Home installation is for the 102, it's not for Jelmyto. I think that's really important. I think there may have been some confusion around that. So what we're looking at and the purpose of doing that was a couple of fold. One, the installation for 102 is much easier than it is for Jelmyto, given that it's in the lower track. And we think it's really important for patients, for physicians, to understand and for regulators to understand the ease of use 102. So that provide to provide the flexibility of being able to have these installations done at home, that not only broadens the patient population that may be able to get 102. But it also serves to demonstrate the ease of use of 102. So in fairness, we don't expect a large majority of the patients that would probably be a small majority of their -- a small minority of the patients, that would actually end up with using it at home. But we think it's important to do a home installation study. Given what's happened this past year in the pandemic, and some of the challenges we've had is to demonstrate our ability to actually have a therapy that is much easier to give than what you see with TURBT. So those are some of the reasons and rationale for us doing this study. So I hope that helps.

So that's very helpful. One last one here. With respect to the Nephrostomy Tube-based application, I was just wondering if you already had clarity regarding how to pursue this from a regulatory perspective? Or what are the implications with regard to labeling? Or if you think that this is likely to be more pursued or become part of the treatment continuum with respect to the product, from a commercial standpoint, purely on the basis of physician discretion, as it were?

Yeah, the good news is, it's already in our label. So because it was part of this trial, even though no one used it. It's actually in our label today. So we don't need to do any additional regulatory work. We do think that it's an exciting area for us, because if we have found, physicians are able to give it in the clinic and they’re in their office. And so it may be an ease of use. But we don't need to do anything from a regulatory standpoint. We want to be able to share with physicians and other physicians, the experience that some are having with it, which is one of the reason we want to be able to talk about it more and to share experiences. But we don't need to do anything from a regulatory standpoint.

Thank you.

Thank you. Our next question comes from Derek Archila with Stifel. Your line is now open.

Hey, good morning, guys. This is Jacques on for Derek. Thanks for taking our questions. Just a couple from us here. First, regarding formulary approvals. Are there any upcoming ones that could be major drivers? And then if I could fit the last one in here about how you view spending quarter-over-quarter? And what the progression might look like there? Thanks.

So Jeff, why don't you take the formulary question and Molly can follow up with the quarter-over-quarter spending.

Sure. So yes, Jacques. Every quarter every week, we have formulary reviews. We have committees starting to meet again, if they delayed because of the vaccine or COVID. So we have a significant number, still in formulary review and accounts coming on. Every one of those is a huge win, because that you get through that internal process the bureaucracy of the particular account. So it then opens it up for positions within that practice. I will say, for the most part, the major cancer institutions, if not all have already on formulary. But for us to be constantly working through formulary, I see that continuing and opening up accounts. And they will have some significant impact the remainder of the year.

And as it relates to spending quarter-over-quarter for the year. I think, we saw Q1 was a little bit lower, and largely because of COVID, some T&E commercial spends. But we would expect that would continue to ramp for the rest of the year, especially as it relates to the ongoing 102 trial.

Great, thanks. It's very helpful. And congrats on all the progress.

Thank you.

Thank you. Our next question comes from Matt Kaplan with Ladenburg Thalmann. Your line is now open.

Great, thanks. Good morning, guys. Just want to get a little bit more color. I guess, now with 316 sites open up. Can you put that in context for us in terms of the number of sites kind of overall that you would expect to be able to have trained and ready to ready to use Jelmyto?

Jeff?

Sure. So we have -- we target around 1300-1500 accounts. Of which we quartile tile one of our top accounts, 500 to 600. So I'm very pleased with where we are with the major accounts that we wanted to make sure that we had access to early on. That number, as I stated continues to grow, will continue to grow up to that 13 to 15 a peak. And to have the majority or all of those accounts on board. But the 316 continues to grow and those key accounts that we were obviously targeting.

Okay, that's very helpful. Thanks. And then, I guess maybe for Mark. Give us a little bit more color in terms of how the enrollment in ATLAS is going. And sites opening up, you mentioned kind of expectation for one third of the sites in the U.S. and some in Israel on another bulk of sites in Eastern Europe. Can you give us a sense in terms of where you are in opening those sites and enrollment in the study?

Matt, thank you. We actually have not released specific information either about patient numbers or site numbers. But I can tell you that we're charging along, working hard to open up the sites that we predicted we would, both in the U.S. and in Europe. And that is in fact happening. We've had calls as recently as yesterday with European regulators regarding the protocols. So we are moving forward. And I'm pleased with the way that is going. But Liz wants to comment further. And I think that's probably about as much as I can see right now.

Yeah, I think, Mark is right. It's typical. It's actually what I'm seeing here is now that we're kind of starting to open sites is very typical than what you would normally see in a clinical study. You will get to a point where we start to see a hockey stick, we're not there yet. But we are seeing sites coming on every week. So we'll be able to be in a position -- better position and give more of an update later this year. But thanks, Matt.

Yeah that’s helpful. Thanks. And then our last question, I guess, more on kind of get a sense of your business development. I guess to two areas in term of questioning. In terms of RTGel technology and business development there. And how you're thinking about that? And then I guess now with your commercial operations up and running fully in your oncology, urology. I guess what are your plans from business development point of view to bring in potentially new products as well, externally?

Yeah. Great question. On the RTGel, we absolutely talk to mostly academic centers, but we have had a couple of companies say, hey, there might be something interesting either for us in their portfolio or for them in their portfolio. So we are always looking for potential areas, even outside of uro-oncology that others are interested in nothing, that's far enough along for us to have discussion about. We are excited about one particular area that we're working with and one academic institution about when at the appropriate time, we'll be able to share that information that sort of expands the use of our technology. As far as bringing products in, we absolutely are looking for them all the time. We want to make sure we’re staying within our spaces, right of uro-oncology and in specialty oncology, both with and without RTGel. So, we constantly are doing something. We're in the process right now of doing another screen. They're hard to find. But we absolutely would love to leverage our team, our company, our infrastructure. We believe we have the right infrastructure, the right people, the right expertise to add to our portfolio. But we also are not going -- we don't need it. So it's not a situation where we need something to come in. We would like to add more to our portfolio. As I mentioned before, we've right now have three different medicines and three different stages of development. But of course, we'd love to add more either again in uro-oncology, or a specialty oncology. So we continue to look and hope that we can bring something in. But we want to make sure it's something that will advance standard of care. And it’s in the right space for us. But, always looking if you ever run across anything have any suggestions, please feel free to forward them along.

Great, thanks. Thanks for taking the questions. And congrats on good results in the quarter.

Thanks, Matt.

Thank you. Our next question comes from Paul Choi with Goldman Sachs. Your line is now open.

Hi, thank you. Good morning. And thank you for taking our questions. One commercial one for Jeff to start. Just with regard to time, -- getting time out of therapy. Jeff, I was wondering if you may just provide a little bit of color as to how over the course of the quarter, the times on patients start between the script and then actually getting the installation has progressed. And, right now, the primary sort of headwind is either just COVID, or payer approval and so forth. Any color there would be great. And then I have a follow up.

Yeah, well great question. So I'll say that it continues to get faster. On average it’s four to five weeks to get an account up and running. A lot depends on that account. If there's a formulary process, we need to go through it could take longer. And I will say that when I said it gets faster once an account is up and running, that number goes down to about two weeks, sometimes even less. So once they've gotten through everything have been trained on our end, gotten through the formulary process. So accounts that are on board, bring that four to five week average significantly down. But yes, there's still accounts that if a formulary meeting isn't for a couple months, will take a little bit longer. But the average is coming down from a setup standpoint.

Okay, great. That's very helpful. And then I had one pipeline question for Mark, just regarding any expanded or updated thoughts on the GBM program. And just how you're thinking about positioning the drug there. And your thoughts on an early basket trial or early trial design in terms of patient groups? Are you thinking mostly operative or perioperative population? Or are you thinking perhaps about doing combinations with like device therapies like the OPTIM [ph] device?

Great question. And I think, to be quite honest, although we've had very intriguing conversations with our collaborators at Johns Hopkins about these very issues. It is a little premature for me to tell you about where this is really go once it becomes a clinical project. Because right now we're focusing on demonstrating the preclinical value of this thinking, which we think is going to be very interesting. But I think we need to provide a little bit more data before we move toward answering those questions. But we're certainly thinking about them. And I think, ultimately, I hope we get where you want to go with this. But I think it's too early to say.

Okay, thank you, Mark. And thanks for taking our questions.

Thanks, Paul.

Thank you. Our next question comes from Leland Gershell with Oppenheimer. Your line is now open.

Hey, good morning, everyone. Thanks for taking my questions. Once as the agenda Jelmyto launch rolls forward and has more experience in the field. Just wanted to ask if you are aware of the kinds of patients who are getting the product? Are there certain characteristics of anatomy? Is it surgical eligibility? Or is it kind of across the board and more dependent on just those centers and those providers who are able to have access to give the product? Just wanted to get more color on how the population of patients and their characteristics? I guess for anybody who can answer. Thank you.

Yeah, Jeff, I think is probably the best person to answer that question, Jeff?

Sure. So, at launch, it was probably more of the recurrent pool of patients of late. It's across the board, as you stated. So we're seeing physicians use it in an unresectable population, or even resectable, they'll go in, remove what they can see, and then come back a week or two later, with six doses to clean up, what they can't see or can't get. So it's fully what I expected at launch. The first few months where patients were recurring, they knew their cancer was back physicians wanted a different treatment options. And as we evolve, and we go in, and we get face-to-face interaction, and we basically promote the entire indication, physician start to think about other patients. And we're starting to see that, that could benefit Jelmyto.

Great, thank you. That's helpful. Thanks very much.

Thanks, Leland.

Thank you. I'm not showing any further questions at this time. I would now like to turn the call back over to Liz Barrett for closing remarks.

Thank you, operator. And thanks to everyone. As we look forward to the remainder of 2021 we're very enthusiastic, we feel like we're having a significant impact on patients. And we're seeing that as we talked about with Jelmyto. We have the people we have the financial strength at Jelmyto and our pipeline forward. So we'll continue to provide updates throughout the year as we execute on our long-term strategy. So I just want to say thank you to everybody for your time today your interest and support. So operator, you may now disconnect. Thank you.

This concludes today's conference call. Thank you for participating. You may now disconnect.